Tablet Capping And Lamination

Capping or lamination is an unsolved common problem in tablet manufacturing.

Tablet capping and lamination.

This challenge can be overcome by doing a pre compression as well as reducing the compression and minimizing the tableting rate. Using acetaminophen containing formulations we examined the potential use of a compaction simulator as a material sparing tool to predict capping occurrence under commercial. Root causes of lamination. Lamination is whenever tablet is breaking or separating anywhere rather than top if is separating from top it is capping.

Before rectifying be sure it is lamination where is the problem surface of tablet below the top layer or bottom of tablet. First lamination is caused by air being trapped in the tablet especially among the granules or particles. Machine related in this article we will be discussing five major causes of this problem and remedies for them. Lamination is also caused by the presence of a large amount of fines in the granulations.

Better understand the tablet capping lamination phenomenon. Fines are small dust particles which. Although the method is widely used there are still significant challenges with achieving a high quality compact. Tablet capping and lamination powder compaction is widely used to produce pharmaceutical tablets and is referred to as a tabletting process.